Scientist III
Location: Rockville
Posted on: June 23, 2025
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Job Description:
Description Who is USP? The U.S. Pharmacopeial Convention (USP)
is an independent scientific organization that collaborates with
the world's top authorities in health and science to develop
quality standards for medicines, dietary supplements, and food
ingredients. USP's fundamental belief that Equity = Excellence
manifests in our core value of Passion for Quality through our more
than 1,300 hard-working professionals across twenty global
locations to deliver the mission to strengthen the supply of safe,
quality medicines and supplements worldwide. At USP, we value
inclusivity for all. We recognize the importance of building an
organizational culture with meaningful opportunities for mentorship
and professional growth. From the standards we create, the
partnerships we build, and the conversations we foster, we affirm
the value of Diversity, Equity, Inclusion, and Belonging in
building a world where everyone can be confident of quality in
health and healthcare. USP is proud to be an equal employment
opportunity employer (EEOE) and affirmative action employer. We are
committed to creating an inclusive environment in all aspects of
our workan environment where every employee feels fully empowered
and valued irrespective of, but not limited to, race, ethnicity,
physical and mental abilities, education, religion, gender
identity, and expression, life experience, sexual orientation,
country of origin, regional differences, work experience, and
family status. We are committed to working with and providing
reasonable accommodation to individuals with disabilities Brief Job
Overview This is a hands-on, analyst position in USPs NMR
Laboratory. The scientist will be an integral member of the nuclear
Magnetic Resonance Spectroscopy (NMR) team and will assist in the
execution of structural elucidation of reference materials by NMR
and purity determination by quantitative NMR and Circular Dichroism
(CD) instruments including designing and executing experiments
supporting reference materials evaluations, product investigations
and other relevant programs in the laboratory. This work includes
development, execution and/or validation of complex analytical
procedures supporting the identity, strength, and purity of the
evaluated material. Reference materials encompass a diverse group
including small molecules, biologics, excipients, oligosaccharides,
vitamins, complex mixtures, peptides, and polymers, providing a
broad range of experience for the scientist in this position.
Scientist must have mastered many common NMR and CD techniques
(preferably) with the laboratory and be able to contribute their
own observations and input to difficult projects. The successful
candidate can direct, troubleshoot, and share insights on complex
projects, while drawing independent conclusions about the results
and determining how to proceed with the project. The successful
candidate demonstrates the ability to lead projects to completion
with a high degree of scientific expertise How will YOU create
impact here at USP? In this role at USP, you contribute to USP's
public health mission of increasing equitable access to
high-quality, safe medicine and improving global health through
public standards and related programs. In addition, as part of our
commitment to our employees, Global, People, and Culture, in
partnership with the Equity Office, regularly invests in the
professional development of all people managers. This includes
training in inclusive management styles and other competencies
necessary to ensure engaged and productive work environments. The
Scientist III, NMR has the following responsibilities: About 70 %
of the incumbent work is expected to be at the bench level. In this
capacity the NMNR scientist: Actively performs testing at the
bench, taking responsibility for interpreting, report writing, as
well as ensuring the project is completed in a timely manner.
Provides hands-on NMR sample preparation, multinuclear as well as
2D NMR data acquisition and processing using 600 MHz, 500 MHz, and
400 MHz spectrometers equipped with cryoprobes. Focuses on
assessing data interpretation and analyzing the structures of small
molecules, excipients, and polymers in support of the USP
catalogue. Works independently and may help others to develop and
validate methodologies for the analysis of drug substances, drug
products, dietary substances, excipients, and other relevant
products. Demonstrates solid scientific approach to analysis in the
laboratory. Troubleshoots difficult/unusual lab problems
independently; collaboratively assists others with troubleshooting.
Conducts planning of research and development required for all
projects; reviews literature; acts as a resource to others in the
planning of projects and analysis of results. Works with the other
team members collaboratively to develop effective testing plans and
experimental designs. About 5% of the incumbent work would be
related to the management of NMR instruments: cryogen filling and
calibration, advising the metrology personnel, and/or assisting
vendor technicians, etc. About 10% of the incumbent work may
consist of training other instrument users, mentoring staff in the
proper use of the NMR instruments, reviewing reports, and providing
technical support within the organization when needed. About 10% of
the incumbent work may be related to the experimental process and
related documentation (review and revising of Standard Operating
Procedures, proposing process improvements, etc.) and peer reviewed
manuscripts submissions of scientific work. About 5% of the
incumbent work may consist of adopting techniques particularly
Circular Dichroism (CD) method development and training activities
on work relating to reference materials and CRAFT software
applications of NMR data Who is USP Looking For? The successful
candidate will have a demonstrated understanding of our mission,
commitment to excellence through inclusive and equitable behaviors
and practices, ability to quickly build credibility with
stakeholders, along with the following competencies and experience:
Ph.D. in Polymer chemistry or Natural products isolation and
structural elucidation or peptide related fields involved in NMR
based thesis development with either graduate or postdoctoral
research (0-2 years) exclusive experience polymer end group
analysis, chain length and molecular weight determinations,
excipient materials, and/or in natural products structural
characterization and conformational analysis, peptide structure
confirmation at natural abundance by testing primarily using
solution NMR spectroscopy. Experience working in the pharmaceutical
industry and/or academia strongly preferred. Working knowledge of
methods and procedures, and expertise in calibrating and operating
NMR equipment (Bruker/ JEOL) required. Quantitative NMR experience
for determining purity. Must have demonstrated success in utilizing
modern methods of NMR techniques for chemical structure
characterizations. Relevant experience in preparation of organic
samples for NMR data collection, as well as data interpretation as
applied to structural verification and confirmation. Ability to
maneuver and handle projects between two instrumental platforms
(Bruker and JEOL) is essential. Takes personal responsibility to
ensure work is delivered on time and is the highest possible
quality with minimal supervision. Skill to anticipate, troubleshoot
and solve technical problems. Ability to implement novel NMR
methods from literature is highly desirable. Familiar with TopSpin
and Delta JEOL software for data acquisition and processing. Strong
communication and presentation skills, both verbal and written.
Additional Desired Preferences Use additional software such as ACD
and CRAFT for NMR data analyses. Experience with Circular Dichroism
applications for small molecules. Supervisory Responsibilities
None, this is an individual contributor role. Benefits USP provides
the benefits to protect yourself and your family today and
tomorrow. From company-paid time off and comprehensive healthcare
options to retirement savings, you can have peace of mind that your
personal and financial well-being is protected. Compensation Base
Salary Range: USD $85,500.00 - $111,250.00 annually. Target Annual
Bonus: % Varies based on level of role. Individual compensation
packages are based on various factors unique to each candidates
skill set, experience, qualifications, equity, and other
job-related reasons. Note: USP does not accept unsolicited resumes
from 3rd party recruitment agencies and is not responsible for fees
from recruiters or other agencies except under specific written
agreement with USP. Equal Opportunity Employer/Protected
Veterans/Individuals with Disabilities This employer is required to
notify all applicants of their rights pursuant to federal
employment laws. For further information, please review the Know
Your Rights (https://www.eeoc.gov/poster) notice from the
Department of Labor. Job Category Chemistry & Scientific Standards
Job Type Full-Time
Keywords: , Arlington , Scientist III, Science, Research & Development , Rockville, Virginia